The group of carbazoles confirmed nanomolar affinities for the CB1 receptor and behaved as total agonists in cAMP accumulation assays. They circumvent the structural capabilities described in the NpSG by scaffold hopping. This new course of synthetic cannabinoids needs to be even further analyzed to fully look into its SARs https://am220108631.qodsblog.com/31139486/am-2201-fundamentals-explained